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Substance Use, Health and Behavior Lab (Meier)

Keywords:  cannabis/marijuana; substance use; psychosis; retinal imaging 

Lab Research Area:

We seek to understand the causes, course, and consequences of problematic substance use through longitudinal epidemiological and case-control studies. Current research projects include (1) understanding links between cannabis use, psychotic-like experiences, and vascular health; (2) documenting the prevalence and correlates of vaping marijuana among college students; and (3) testing whether older adult marijuana users show neuropsychological impairment and functional impairment in everyday life.

Medical Marijuana Users- Earn $95 for a Research Study

Researchers from the ASU Department of Psychology are looking for medical marijuana users between the ages of 18-30 with an Arizona medical marijuana card to participate in a study. The study compares the immediate effects of your at-home use of different types of marijuana and takes approximately 10 hours over the course of 1 week. During that week, you will be asked to come to the lab for a two hour visit, and you will receive several text messages per day asking you to complete short surveys related to your marijuana use and marijuana effects. Participation is voluntary.

Please email THCResearch50@gmail.com or leave a voicemail at (480) 727-5799 with times you are available for a 15 minute phone conversation to determine your eligibility.

Join the Lab!

If you are interested in becoming a research assistant in the Substance Use, Health, and Behavior Lab during academic year 2017 - 2018, please send the following information to Dr. Meier:

1. Your name, year in school, major, and email address
2. Could you be a member of the lab for at least two semesters?
3. Are you interested in graduate school? What do you want to do for a career?
4. Why do you want to join the lab?
5. What can you bring to the team?

 

 

Lab Director and Principal Investigator: Madeline Meier, PhD, Assistant Professor

Dr. Madeline Meier joined the Psychology Department faculty at ASU in 2013. Her research seeks to understand the causes, course, and consequences of problematic substance use through longitudinal epidemiological and case-control studies. Her recent work on marijuana has shown that (i) persistent marijuana use across the high-school years is associated with lower grade-point-average and lower SAT scores in 12th grade, (ii) adolescent-onset persistent marijuana use is associated with IQ decline from childhood to adulthood, (iii) persistent marijuana use from adolescence to adulthood is associated with social and economic problems in early midlife, including workplace and relationship problems, downward socioeconomic mobility, and financial difficulties, and (iv) persistent marijuana use from adolescence to adulthood is generally not associated with physical health problems in early midlife (lung function, systemic inflammation, and metabolic health). Dr. Meier’s work documenting the neuropsychological, academic, social, economic, and physical health consequences of cannabis use is being used by policy makers, public interest groups, psychologists, and physicians. Curriculum Vitae.

Current Graduate Students

Melanie Hill, Doctoral Student, Clinical Psychology, Department of Psychology
Melanie earned her B.A. in psychology from UC Berkeley, where she studied sleep and emotion regulation. Currently, she is interested in how coping and emotion regulation processes impact risk for substance use in college students. Melanie hopes this line of research will promote academic success and mental well-being for adolescents and young adults.

Connor Jones, Doctoral Student, Clinical Psychology, Department of Psychology
Connor received his BS in psychology from the University of Washington in 2013. His research interests involve investigating risk factors related to substance use and co-occurring psychopathological problems. His long-term research goals are to develop preventative strategies and interventions tailored to comorbid populations.

Sarah Okey, Doctoral Student, Clinical Psychology, Department of Psychology Sarah obtained her B.A. in psychology from The Ohio State University in 2015. Her research interests include examining the short and long-term consequences of cannabis use in an effort to help inform public policy and develop effective interventions for problematic substance use.

 

Current Undergrad Research Assistants

Sasha Rife
Mikayla Isosaki
Isabelle Oboza
Kayla Reents
Nathalie Tinoco
Matthew Broussard
Jessica Siegel
William Conlin
Allie Drake

Join the Lab!

If you are interested in becoming a research assistant in the Substance Use, Health, and Behavior Lab during academic year 2016 - 2017, please send the following information to Dr. Meier:

1. Your name, year in school, major, and email address
2. Could you be a member of the lab for at least two semesters?
3. Are you interested in graduate school? What do you want to do for a career?
4. Why do you want to join the lab?
5. What can you bring to the team?

Select Publications

Below are a sample of recent publications from Dr. Meier's research and lab. A more complete listing may be found in Dr. Meier's curriculum vitae.

2017

 Meier, M.H., Caspi, A., Danese, A., Fisher, H.L., Houts, R., Arseneault, L., & Moffitt, T.E. Associations between adolescent cannabis use and neuropsychological decline: A longitudinal, cotwin-control study. Addiction.

Meier, M.H.  Associations between butane hash oil use and cannabis-related problems. Drug and Alcohol Dependence.

Meier, M.A., & Meier, M.H. Clinical implications of a general psychopathology factor: A cognitive-behavioral transdiagnostic group treatment for community mental health. Journal of Psychotherapy Integration

2016

Meier, M.H., Caspi, A., Cerdá, M., Hancox, R.J., Harrington, H.L., Houts, R., Poulton, R., Ramrakha, S., Thomson, W.M., & Moffitt, T.E. (2016). Associations between cannabis use and physical health problems in early midlife: A longitudinal comparison of persistent cannabis versus tobacco users. JAMA Psychiatry, 73, 731-740. Second most talked about paper of 2016 in JAMA Psychiatry. http://read.alerts.jamanetwork.com/csb/Public/show/dxney--b9kyo-1b69xst6

Meier, M.H., Hall, W., Caspi, A., Belsky, W., Cerdá, M., Harrington, H.L., Houts, R., Poulton, R., & Moffitt, T.E. (2016). Which adolescents develop persistent substance dependence in adulthood? Using population-representative longitudinal data to inform universal risk assessment. Psychological Medicine, 46, 877-889.

Meier, M.H., *Hill, M.L., & Breitborde, N.J.K. (2016). Retinal Imaging: A new tool for studying underlying liability to cardiovascular disease in schizophrenia. Current Psychiatry Reviews, 12, 326-334.

*Jones, C.B.,* Hill, M.L., Pardini, D., & Meier, M.H. (2016). Prevalence and correlates of vaping cannabis in a sample of young adults.Psychology of Addictive Behaviors, 30, 915-921.

Breitborde, N.J.K. & Meier, M.H. (2016). Cognition in first-episode psychosis: from phenomenology to intervention. Current Psychiatry Reviews, 12, 306-318. 

Volkow, N.D., Swanson, J.M., Evins, A.E., DeLisi, L.E., Meier, M.H., Gonzalez, R., Bloomfield, M.A., Curran, H.V., & Baler, R. (2016). Effects of cannabis use on human behavior, including cognition, motivation, and psychosis: A review. JAMA Psychiatry, 73, 292-297.

Cerdá, M., Moffitt, T.E., Meier, M.H., Harrington, H.L., Houts, R., Ramrakha, S., Hogan, S., Poulton, R., & Caspi, A. (2016). Persistent cannabis dependence and alcohol dependence represent risks for midlife economic and social problems: A longitudinal cohort study. Clinical Psychological Science4, 1028-1046.

2015 

Meier, M.H., *Hill, M.L., *Small, P.S., & Luthar, S.S. (2015). Associations of adolescent cannabis use with academic performance and mental health: A longitudinal study of upper middle class youth. Drug and Alcohol Dependence, 156, 207-212.

Meier, M.H., Gillespie, N.A., Hansell, N.K., Hewitt, A.W., Hickie, I.B., Lu, Y., MacGregor, S., McGrath, J., Medland, S.E., Sun, C., Wong, T.Y., Wright, M., Zhu, G., Martin, N.G., & Mackey, D.A. (2015). Retinal microvessels reflect familial vulnerability to psychotic symptoms: A comparison of twins discordant for psychotic symptoms and controls. Schizophrenia Research, 164, 47-52.

Moffitt, T.E., Houts, R., Asherson, P., Belsky, D.W., Corcoran, D.L., Hammerle, M., Harrington, H.L., Hogan, S., Meier, M.H., Polanczyk, G.V., Poulton, R., Ramrakha, S., Rohde, L.A., Sugden, K., Williams, B., & Caspi, A. (2015). Is adult ADHD a childhood-onset neurodevelopmental disorder? A 4-decade longitudinal cohort study. American Journal of Psychiatry, 172, 967-977.

2014
Meier, M.H., Gillespie, N.A., Hansell, N.K., Hewitt, A.W., Hickie, I.B., Lu, Y., MacGregor, S., Medland, S.E., Sun, C., Wong, T.Y., Wright, M., Zhu, G., Martin, N.G., & Mackey, D.A. (2014). Associations between depression/anxiety symptoms and retinal vessel caliber in adolescents and young adults. Psychosomatic Medicine, 76, 732-738.

Meier, M.H., Moffitt, T.E., Caspi, A., & Poulton, R. (2014). Reply to Bora: Cognitive deficits in schizophrenia follow a neurodevelopmental and neurodegenerative course. American Journal of Psychiatry, 171, 369-370.

Meier, M.H., Caspi, A., Reichenberg, A., Keefe, R.S.E, Fisher, H.L., Harrington, H.L., Houts, R., Poulton, R., & Moffitt, T.E. (2014). Neuropsychological decline in schizophrenia from the premorbid to post-onset period: Evidence from a population-representative longitudinal study. American Journal of Psychiatry, 171, 91-101.

Caspi, A., Houts, R., Belsky, D.W., Goldman-Mellor, S., Harrington, H.L., Israel, S., Meier, M.H., Ramrakha, S., Shalev, I., Poulton, R., & Moffitt, T.E. (2014). The ‘p factor’: One general psychopathology factor in the structure of psychiatric disorders? Clinical Psychological Science, 2, 119-137.

2013
Meier, M.H.a, Shalev, I.a, Moffitt, T.E., Kapur, S., Keefe, R.S.E., Wong, T.Y., Belsky, D.W., Harrington, H.L., Hogan, S., Houts, R., Caspi, A., & Poulton, R. (2013). Microvascular abnormality in schizophrenia as shown by retinal imaging. American Journal of Psychiatry, 170, 1451-1459. aJoint first authors.

Meier, M.H., Caspi, A., Houts, R., Slutske, W., Harrington, H.L., Jackson, K., Belsky, D., Poulton, R., & Moffitt, T.E. (2013). Prospective developmental subtypes of alcohol dependence from age 18 to 32 years: Implications for nosology, etiology, and intervention. Development and Psychopathology, 25, 785-800.

Belsky, D.W., Caspi, A., Goldman-Mellor, S., Meier, M.H., Poulton, R., & Moffitt, T.E. (2013). Is obesity associated with a decline in intelligence quotient during the first half of the life course? American Journal of Epidemiology, 178, 1461-1468.

Belsky, D.W., Moffitt, T.E., Baker, T.B., Biddle, A.K., Evans, J.P., Harrington H.L., Houts, R., Meier, M.H., Sugden, K., Williams, B., Poulton, R., & Caspi, A. (2013). Polygenic risk accelerates the developmental progression to heavy, persistent smoking and nicotine dependence: Evidence from a 4-Decade Longitudinal Study. JAMA Psychiatry, 70, 534-542.

Shalev, I., Moffitt, T.E., Wong, T.Y., Meier, M.H., Ding, J., Cheung, C.Y., Ikram, K.M., Houts, R., Caspi, A., & Poulton, R. (2013). Retinal vessel caliber and lifelong neuropsychological functioning: An investigative tool for cognitive epidemiology. Psychological Science, 24, 1198-1207.

Fisher, H.L., Caspi, A., Poulton, R., Meier, M.H., Houts, R., Harrington, H.L., Arseneault, L., & Moffitt, T. (2013). Specificity of childhood psychotic symptoms for predicting schizophrenia by 38 years of age: A birth cohort study. Psychological Medicine, 43, 2077-2086.

Moffitt, T.E., Meier, M.H., Caspi, A., & Poulton, R. (2013). Reply to Rogeberg and Daly: No evidence that socioeconomic status or personality differences confound the association between cannabis use and IQ-decline. Proceedings of the National Academy of Sciences, 110, E980-E982.

2012
Meier, M.H., Caspi, A., Ambler, A., Harrington, H.L., Houts, R., Keefe, R.S.E., McDonald, K., Ward, A., Poulton, R., & Moffitt, T.E. (2012). Persistent cannabis users show neuropsychological decline from childhood to midlife. Proceedings of the National Academy of Sciences, 109, 2657-2664.

News & More!

Madeline Meier’s marijuana research hits media mainstream!

In collaboration with researchers at Duke University, UC Davis, and others in the UK and New Zealand, Dr. Meier’s recently published study on marijuana usage gains international attention.  Read more on their findings published in JAMA Psychiatry and see the story, “Study says long-term pot use causes poor gum health – but not much else” from The Guardian. Posted June 1, 2016.

Medline PLUS, NIH U.S. National Library of Medicine, Long-Term Pot Use Tied to Gum Disease in Study. June 1, 2016

Washington Post, Chronic marijuana use is about as bad for your health as not flossing, researchers find, June 2, 2016.

Dr. Meier will travel to Bethesda, MD in March 2016 to present research on marijuana and neuropsychological function for the NIH-sponsored meeting, “Marijuana and Cannabinoids: A Neuroscience Research Summit”

Undergraduate students in the lab are learning to use the retinal camera for our research studies on cannabis, psychotic-like experiences, and retinal vascular health (attach photo: “Undergrads retinal imaging”). The retina of the eye offers a window to the condition of the blood vessels in the brain and body. By studying the health of the retinal blood vessels, we can gauge the health of the brain and body blood vessels.

Previous Posts

Dr. Meier's video interview with the National Institute on Drug Abuse, NIDANotes:  Early-Onset, Regular Cannabis Use Is Linked to IQ Decline, August 13, 2013.
Marijuana's Lasting Effects on the Brain, March 2013, Messages from the Director of NIDA, Dr. Nora Volkow

From The Conversation, Teen cannabis use lowers IQ, despite claims to the contrary, Jan 14, 2013
In Nature, Drop in IQ linked to heavy teenage cannabis use; Aug 28, 2012.
Teen pot use linked to later declines in IQ, Associated Press, August 27, 2012